Nature Medicine
Nature Medicine
a year ago

The Aging Biomarker Consortium represents a new era for aging research in China

The Aging Biomarker Consortium represents a new era for aging research in China
Jie Ren, Moshi Song, Weiqi Zhang, Jian-Ping Cai, Feng Cao, Zhongwei Cao, Piu Chan, Chang Chen, Guobing Chen, Hou-Zao Chen, Jun Chen, Xiao-Chun Chen, Weimin Ci, Bi-Sen Ding, Qiurong Ding, Feng Gao, Shaorong Gao, Jing-Dong J. Han, Qi-Yang He, Kai Huang, Zhenyu Ju, Qing-Peng Kong, Ji Li, Jian Li, Jingyi Li, Xin Li, Baohua Liu, Feng Liu, Jun-Ping Liu, Lin Liu, Qiang Liu, Qiang Liu, Xingguo Liu, Yong Liu, Xianghang Luo, Shuai Ma, Xinran Ma, Zhiyong Mao, Jing Nie, Yaojin Peng, Jing Qu, Ruibao Ren, Weihong Song, Zhou Songyang, Liang Sun, Yi Eve Sun, Yu Sun, Mei Tian, Xiao-Li Tian, Ye Tian, Jianwei Wang, Shusen Wang, Si Wang, Wengong Wang, Xia Wang, Xiaoning Wang, Yan-Jiang Wang, Yunfang Wang, Catherine C. L. Wong, Andy Peng Xiang, Yichuan Xiao, Zhi-Xiong Xiao, Zhengwei Xie, Wei Xiong, Daichao Xu, Ze Yang, Jing Ye, Wei Yu, Rui Yue, Cuntai Zhang, Hongbo Zhang, Liang Zhang, Xinchao Zhang, Yong Zhang, Yun-Wu Zhang, Zhuohua Zhang, Tongbiao Zhao, Yuzheng Zhao, Zhongjun Zhou, Dahai Zhu, Weiguo Zou, Gang Pei, Guang-Hui Liu
'Aging biomarkers' refers to scientifically measurable parameters of the aging process; these are age-related changes at cellular, organ and organismal levels that can be applied to predict the transition into a pathological state1. Biomarkers can be classified into six categories: physiological characteristics; imaging traits; histological features; cellular alterations; molecular changes; and secretory factors. These six categories provide a framework for mechanistic studies of the fundamental principles of aging that uncover cellular and molecular insights into regulatory networks that govern the aging process1. In addition to serving as biomarkers, some are often referred to as 'drivers of aging' and may hold potential as intervention targets for slowing down the aging process2,3,4,5.

Publisher URL: https://www.nature.com/articles/s41591-023-02444-y

DOI: 10.1038/s41591-023-02444-y

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