Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking

5 years ago

Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking

Letizia Giampietro, Cristina Maccallini Maccallini, Pasquale Amoia, Barbara De Filippis, Armenio J.M. Moura Barbosa, Rosa Amoroso, Marialuigia Fantacuzzi, Alessandra Ammazzalorso, Antonella Giancristofaro

FXR is a member of the nuclear receptor superfamily, regulates the expression of various genes involved in bile acid, lipid and glucose metabolism. Targeting FXR with small molecules has been...

Publisher URL: http://feeds.rsc.org/~r/rss/MD/~3/bn6qGMRERdg/C8MD00272J

DOI: 2018/MD/C8MD00272J

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