Nature Reviews Neuroscience
Nature Reviews Neuroscience
5 years ago

Modelling microglial function with induced pluripotent stem cells: an update

Modelling microglial function with induced pluripotent stem cells: an update
Thomas M. Piers, Jennifer M. Pocock
It is becoming increasingly apparent that microglia, the immune cells of the CNS, and their peripheral counterparts, macrophages, have a major role in normal physiology and pathology. Recent technological advances in the production of particular cell types from induced pluripotent stem cells have led to an interest in applying this methodology to the production of microglia. Here, we discuss recent advances in this area and describe how they will aid our future understanding of microglia.

Publisher URL: https://www.nature.com/articles/s41583-018-0030-3

DOI: 10.1038/s41583-018-0030-3

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